anti-NQO1 antibody

anti-NQO1 antibody for Western blot,ICC/IF,Immunoprecipitation,Flow cytometry and Human,Mouse,Rat

publication_link Publication1


Product Description Rabbit Polyclonal antibody recognizes NQO1
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NQO1
Antigen Species Human
Immunogen Synthetic peptide derived from Human NQO1.
Conjugation Un-conjugated
Alternate Names DTD; QR1; DHQU; DIA4; NMOR1; NMORI; NAD(P)H dehydrogenase [quinone] 1; EC; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:1000 - 1:5000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SH-SY5Y
Observed Size ~ 32 kDa


Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 1728 Human NQO1

GeneID: 18104 Mouse NQO1

GeneID: 24314 Rat NQO1

Gene Symbol NQO1
Gene Full Name NAD(P)H dehydrogenase, quinone 1
Background This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Function The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Highlight Related Antibody Duos and Panels:
ARG30345 Keap1-Nrf2-ARE Antibody Panel
Related products:
NQO1 antibodies; NQO1 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Keap1-Nrf2-ARE antibody panel is launched
Calculated MW 31 kDa

Images (2) Click the Picture to Zoom In

  • ARG43340 anti-NQO1 antibody ICC/IF image

    Immunofluorescence: MCF7 cells stained with ARG43340 anti-NQO1 antibody.

  • ARG43340 anti-NQO1 antibody WB image

    Western blot: SH-SY5Y cell lysate stained with ARG43340 anti-NQO1 antibody.

Specific References

Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data

WB / Human

Wanpeng Wang et al.
Front Immunol.,  (2023)