ARG30337

Ferroptosis / Oxytosis Antibody Panel

publication_link Publication6

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG57998 anti-SLC7A11 / xCT antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IP, WB 20 μl
ARG41400 anti-GPX4 antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, WB 20 μl
ARG23717 anti-4 Hydroxynonenal antibody [12F7] Mouse mAb Other ELISA, ICC/IF, IHC-P, WB 20 μg

Overview

Product Description Ferroptosis/Oxytosis Antibody Panel is an all-in-one solution to make research of ferroptosis and oxytosis easy and economic. This antibody panel comprises molecular markers of ferroptosis/oxytosis GPX4 and xCT antibodies and lipid peroxidation marker 4-HNE antibody. This antibody panel is the best solution to study ferroptosis and oxytosis in human, mouse, and rat samples.

Related news:
Ferroptosis/Oxytosis Antibody Panel is launched
Therapeutic strategies against PDAC
Target Name Ferroptosis / Oxytosis
Alternate Names Ferroptosis / Oxytosis antibody; 4 Hydroxynonenal antibody; 4-HNE antibody; GPX4 antibody; SLC7A11 / xCT antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Panel for Ferroptosis / Oxytosis
Highlight Related products:
SLC7A11 antibodies;
GPX4 antibodies; GPX4 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Hydroxynonenal antibodies; Hydroxynonenal ELISA Kits; Hydroxynonenal Duos / Panels; Anti-Mouse IgG secondary antibodies;

Images (8) Click the Picture to Zoom In

  • ARG23717 anti-4 Hydroxynonenal antibody [12F7] IHC-P image

    Immunohistochemistry: Mouse testis stained with ARG23717 anti-4 Hydroxynonenal antibody [12F7] at 1:50 dilution.

    From Lipeng Li et al. FDX1 regulates leydig cell ferroptosis mediates PM2.5-induced testicular dysfunction of mice (2023), doi: 10.1016/j.ecoenv.2023.115309, Fig. 4A1.

  • ARG57998 anti-SLC7A11 / xCT antibody WB image

    Western blot: Mouse Testis stained with ARG57998 anti-SLC7A11 / xCT antibody at 1:1000 dilution.

    From Lipeng Li et al. Ecotoxicol Environ Saf (2023), doi: 10.1016/j.ecoenv.2023.115309, Fig. 2F1.

  • ARG57998 anti-SLC7A11 / xCT antibody WB image

    Western blot: 20 μg of HeLa cell lysate stained with ARG57998 anti-SLC7A11 / xCT antibody at 1:1000 dilution.

  • ARG41400 anti-GPX4 antibody WB image

    Western blot:: Mouse Testis stained with ARG41400 anti-GPX4 antibody at 1:1000 dilution.

    From Lipeng Li et al. Ecotoxicol Environ Saf (2023), doi: 10.1016/j.ecoenv.2023.115309, Fig. 2F1.

  • ARG41400 anti-GPX4 antibody WB image

    Western blot: 20 μg of Mouse testis and Rat testis lysates stained with ARG41400 anti-GPX4 antibody at 1:1000 dilution.

  • ARG23717 anti-4 Hydroxynonenal antibody [12F7] ICC/IF image

    Immunofluorescence: HEK293 cells fixed with 5% Formaldehyde (5 min). Cells were stained with ARG23717 anti-4 Hydroxynonenal antibody [12F7] at 1:50 for 30-60 min at RT. Magnification: 20X (2X Zoom). (A,C,E,G): Untreated. (B,D,F,H): Cells cultured overnight with 50 µM H2O2. (A,B) DAPI (blue) nuclear stain. (C,D) Phalloidin Alex Fluor 633 F-Actin stain. (E,F) Primary antibodies. (G,H) Composite.

  • ARG23717 anti-4 Hydroxynonenal antibody [12F7] WB image

    Western blot: 0.5 µg of BSA, 0.5 µg of 4-hydroxyl nonenal-BSA, 2.0 µg of 4-hydroxy nonenal-BSA, 0.5 µg of 4-hydroxy-2-hexenal and 2.0 µg of 4-hydroxy-2-hexenal stained with ARG23717 anti-4 Hydroxynonenal antibody [12F7] at 1:1000 for 2 hours at RT.

  • ARG57998 anti-SLC7A11 / xCT antibody WB image

    Western blot: 20 μg of Mouse liver lysate stained with ARG57998 anti-SLC7A11 / xCT antibody at 1:1000 dilution.

Specific References

Oyster-Derived Tyr-Ala (YA) Peptide Prevents Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Suppressing Inflammatory, Apoptotic, Ferroptotic, and Pyroptotic Signals

ARG23717: WB / Mouse ARG57998: WB / Mouse ARG41400: WB  / Mouse

Adrian S Siregar et al.
Mar Drugs.,  (2021)

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PM2.5 exposure triggers cell death through lysosomal membrane permeabilization and leads to ferroptosis insensitivity via the autophagy dysfunction/p62-KEAP1-NRF2 activation in neuronal cells

ARG57998: WB / Mouse

Min Wei et al.
Ecotoxicol Environ Saf,  (2022)

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Fermented and Aged Ginseng Sprouts ( Panax ginseng) and Their Main Component, Compound K, Alleviate Asthma Parameters in a Mouse Model of Allergic Asthma through Suppression of Inflammation, Apoptosis, ER Stress, and Ferroptosis

ARG23717, ARG41400, ARG57998: WB / Mouse

Ji Hyeon Ryu et al.
Antioxidants (Basel),  (2022)

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IFNγ enhances ferroptosis by increasing JAK‑STAT pathway activation to suppress SLCA711 expression in adrenocortical carcinoma

ARG57998: WB, ICC/IF / Human

Xinbo Yu et al.
Oncol Rep.,  (2022)

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Liraglutide attenuates hepatic iron levels and ferroptosis in db/db mice

ARG23717: WB / Mouse

Ji-Xian Song et al.
Bioengineered.,  (2022)

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Liraglutide Alleviates Cognitive Deficit in db/db Mice: Involvement in Oxidative Stress, Iron Overload, and Ferroptosis

ARG57998: WB / Mouse

Ji-Ren An et al.
Neurochem Res.,  (2022)

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