ARG30331

NLRP3 Inflammasome Antibody Panel

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Component

Cat No Component Name Host clonality Reactivity Application Package
ARG40539 anti-NALP3 / Cryopyrin antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 20 μl
ARG66211 anti-ASC / TMS1 antibody Rabbit pAb Hu, Ms WB 20 μl
ARG57293 anti-Caspase 1 antibody Rabbit pAb Hu, Ms ICC/IF, IHC-P, IP, WB 20 μl
ARG10112 anti-GAPDH antibody [6C5] Mouse mAb AGMK, Bb, Cat, Chk, Dog, Fsh, Hm, Hu, Mk, Ms, Pig, Rb, Rat, Xenopus laevis, Zfsh ELISA, ICC/IF, IHC-Fr, WB 20 μg

Overview

Product Description NLRP3 Inflammasome Antibody Panel is an all-in-one solution to make the research of NLRP3 inflammasome easy and economic. This antibody panel comprises antibodies against the key components of NLRP3 inflammasome including NLRP3, ASC, and Caspase-1. Moreover, a loading control antibody against GAPDH is also included. This panel is the best solution for studying NLRP3 Inflammasome.

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Target Name NLRP3 Inflammasome
Alternate Names NLRP3 Inflammasome antibody; GAPDH antibody; NALP3 / Cryopyrin antibody; Caspase 1 antibody; ASC / TMS1 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Images (12) Click the Picture to Zoom In

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: 1) U87-MG 2) HepG2 3) rat brain 4) rat heart 5) rat ovary stained with ARG10112 anti-GAPDH antibody [6C5] at 1:2000 dilution.

  • ARG10112 anti-GAPDH antibody [6C5] ICC/IF image

    Immunofluorescence: 100% Methanol fixed (RT, 10 min) HeLa cells stained with ARG10112 anti-GAPDH antibody [6C5] (green) at 1:200 dilution.

    Secondary antibody: ARG55393 Goat anti-Mouse IgG (H+L) antibody (FITC)

  • ARG57293 anti-Caspase 1 antibody WB image

    Western blot: 10 µg of HeLa and 20 µg of Mouse brain lysates stained with ARG57293 anti-Caspase 1 antibody at 1:1000 dilution.

  • ARG57293 anti-Caspase 1 antibody WB image

    Western blot: 25 µg of cell lysate from PMA treated THP-1 cells were stained with ARG57293 anti-Caspase 1 antibody at 1:1000 dilution.

  • ARG57293 anti-Caspase 1 antibody ICC/IF image

    Immunofluorescence: Raw264.7 cells stained with ARG57293 anti-Caspase 1 antibody at 1:100 dilution.

  • ARG57293 anti-Caspase 1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG57293 anti-Caspase 1 antibody at 1:100 dilution.

  • ARG40539 anti-NALP3 / Cryopyrin antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse lung stained with ARG40539 anti-NALP3 / Cryopyrin antibody at 1:100 dilution.

  • ARG66211 anti-ASC / TMS1 antibody WB image

    Western blot: 40 µg of HL60, A549, Raji and RAW264.7 cell lysates stained with ARG66211 anti-ASC / TMS1 antibody at 1:500 dilution.

  • ARG40539 anti-NALP3 / Cryopyrin antibody WB image

    Western blot: 25 µg of Mouse thymus lysate stained with ARG40539 anti-NALP3 / Cryopyrin antibody at 1:1000 dilution.

  • ARG57293 anti-Caspase 1 antibody IP image

    Immunoprecipitation: 200 µg extracts of THP-1 cells Immunoprecipitated and stained with ARG57293 anti-Caspase 1 antibody at 1:1000 dilution.

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: 1) U87-MG 2) MCF-7 3) A549 4) DU145 5) SW480 6) rat brain 7) rat stomach 8) rat ovary stained with ARG10112 anti-GAPDH antibody [6C5] at 1:5000 dilution.

  • ARG10112 anti-GAPDH antibody [6C5] WB image

    Western blot: 1) MCF-7 2) DU-145 3) A549 4) H1299 5) HCT116 6) HepG2 7) HUVEC stained with ARG10112 anti-GAPDH antibody [6C5] at 1:1000 dilution.

Specific References

Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages

ARG40539: WB / Human

Xionghui Ding et al.
Nat Commun.,  (2021)

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