ARG30230

Phospho Integrin beta 3 Antibody Panel (Total, pY773, pY785)

Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG51564 anti-CD61 / Integrin beta 3 phospho (Tyr773) antibody Rabbit pAb Hu, Ms WB, IHC-P 50 μl
ARG51763 anti-CD61 / Integrin beta 3 phospho (Tyr785) antibody Rabbit pAb Hu, Ms WB 50 μl
ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) Mouse mAb Hu WB 50 μl
ARG65350 Goat anti-Mouse IgG antibody (HRP) Goat pAb Ms ELISA, IHC-P, WB 50 μl
ARG65351 Goat anti-Rabbit IgG antibody (HRP) Goat pAb Rb ELISA, IHC-P, WB 50 μl

Overview

Product Description

Cells recognize and respond to their extracellular environment through transmembrane receptors such as integrins, which physically connect the extracellular matrix to the cytoskeleton. Integrins provide the basis for the assembly of intracellular signaling platforms that link to the cytoskeleton and influence nearly every aspect of cell physiology. The integrin beta 3 protein mediates platelet adhesion to immobilized fibrinogen. Adhesion to fibrinogen induced rapid phosphorylation of Integrin beta 3 on Tyr773 and Tyr785 residues, which was reduced by Nitrogen Oxide in a cGMP independent manner. Oberprieler et al. 2007. FEBS Lett 581(7) Legate and Fassler. J Cell Sci 122: 187-98

Target Name Integrin beta 3
Alternate Names Phospho Integrin beta 3 antibody; CD61 / Integrin beta 3 phospho (Tyr773) antibody; CD61 / Integrin beta 3 phospho (Tyr785) antibody; CD61 / Integrin beta 3 antibody (N-term)

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Panel for Phospho Integrin beta 3 (Total, pY773, pY785)
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody

Images (4) Click the Picture to Zoom In

  • ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) WB image

    Western blot: 25 µg of Leukocyte lysate stained with ARG54044 anti-CD61 / Integrin beta 3 antibody (N-term) at 1:1000 dilution.

  • ARG51564 anti-Integrin beta 3 phospho (Tyr773) antibody WB image

    Western Blot: extracts from 293 cells stained with anti-Integrin beta 3 (phospho Tyr773) antibody ARG51564 and the same antibody preincubated with blocking peptide.

  • ARG51564 anti-Integrin beta 3 phospho (Tyr773) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-Integrin beta 3 (phospho Tyr773) antibody ARG51564 (left) or the same antibody preincubated with blocking peptide (right).

  • ARG51763 anti-Integrin beta 3 phospho (Tyr785) antibody WB image

    Western Blot: extracts from HUVEC cells stained with anti-Integrin beta 3 (phospho Tyr785) antibody ARG51763 and the same antibody preincubated with blocking peptide .