Tools for studying Exosomes

Tools for studying Exosomes


Exosomes, the extracellular vesicles secreted by all cells, have the ability to shuttle active cargoes between cells and facilitate intercellular communication. Exosomes are present in body fluids including blood, urine, saliva, and cultured medium of cell cultures.
Evidences accumulated that exosomes implicate in various diseases including cancer metastasis and neurodegeneration diseases. There is a growing interest in the clinical and therapeutic applications of exosomes.
A therapeutic approach of exosomes in specific targeting of oncogenic Kras in pancreatic cancer was reported in Nature recently. Dr. Kamerkar and colleagues found that exosomes carrying shKrasG12D restrain tumor growth, inhibit metastasis and increase survival.
arigo offers excellent antibodies for the isolation, quantification, characterization and analysis of exosomes. The antibodies for studying cancer pathology are also available.


Exosome markers

CD9 antibody [MEM-61] (FITC) (ARG62944) CD63 antibody [NKI/C3] (ARG55941) CD81 antibody [2F7] (PE) (ARG21039)


Product Unconjugated APC Biotin FITC PE
CD9 antibody [MM2/57] ARG21247     ARG21248 ARG21249
CD9 antibody [MEM-61] ARG62943 ARG53912 ARG62942 ARG62944 ARG53913
CD63 antibody [MEM-259] ARG62912 ARG53886 ARG62911 ARG62913 ARG53887
CD81 antibody [M38] ARG62934     ARG62935 ARG53906




Antibodies for studying cancer pathology

Ki-67 antibody [SP6]

Cytokeratin 19 antibody
[A53-B/A2.26] (ARG55966)

ERK phospho (Thr202/Tyr204)
antibody (ARG52277)

Reference: Kamerkar et al., (2017) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature.