SARS-CoV-2 antibodies, proteins, and ELISA kits

SARS-CoV-2 antibodies, proteins, and ELISA kits

 

SARS-CoV-2

The newly identified coronavirus, SARS-CoV-2 (previously known as 2019-nCoV) shares 79.5% sequence identify with SARS-CoV. The viral genome encodes spike, envelope, membrane, nucleocapsid, and multiple non-structural proteins.

arigo offers quality antibodies, proteins, and ELISA kits to facilitate the research of SARS-CoV-2.

 

 

 

 

● Spike protein and ACE2 ●

SARS-CoV-2 cell entry depends on viral spike protein and ACE2 which mediates conversion of Angiotensin II to Angiotensin 1-7. The receptor-binding domain (RBD) of the spike protein is essential for ACE2 binding. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach for COVID-19 treatment.

 

● Spike antibodies 

Product  Clonality Application Cat. No.
SARS-CoV Spike antibody [1A9] Mouse mAb FACS, FuncSt, WB ARG11092
SARS-CoV Spike antibody (N-terminus) Rabbit pAb WB ARG54886
SARS-CoV Spike antibody (Center) Rabbit pAb WB ARG54885
SARS-CoV-2 Spike (S2) antibody Rabbit pAb IHC-P, WB ARG43282
SARS-CoV-2 Spike (RBD) antibody [SQab20178] Mouse mAb ELISA, FACS, ICC/IF, WB ARG66740
SARS-CoV / SARS-CoV-2 Spike (RBD) antibody [CR3022] Human IgG1 ELISA, Neut ARG66739
SARS-CoV / SARS-CoV-2 Spike (RBD) antibody [CR3022] Human IgM ELISA, ICC/IF, Neut ARG66902
SARS-CoV / SARS-CoV-2 Spike (RBD) antibody [CR3022] Human IgA ELISA, Neut ARG66903
SARS-CoV / SARS-CoV-2 Spike (RBD) antibody Rabbit pAb ICC/IF, WB ARG11154

 

● Spike proteins

Product  Expression Cat. No.
SARS-CoV-2 Spike protein (S1 subunit) E. coli ARG70218
SARS-CoV-2 Spike protein (S1 subunit) HEK293 cell ARG70345
SARS-CoV-2 Spike protein (S1 subunit) (Fc-fused) HEK293 cell ARG70353
SARS-CoV-2 Spike protein (RBD) E. coli ARG70219
SARS-CoV-2 Spike protein (RBD) HEK293 cell ARG70343
SARS-CoV-2 Spike protein (RBD) (Fc-fused) HEK293 cell ARG70349

 

● ACE2 antibodies

Product  Reactivity Application Cat. No.
Mouse anti-ACE2 mAb [AC18F] Hu ELISA, FACS, WB ARG42475
Mouse anti-ACE2 mAb Hu WB ARG54802
Rabbit anti-ACE2 mAb [SQab20231] Hu IHC-P ARG66819
Rabbit anti-ACE2 pAb Hu, Ms, Rat IHC-P, IP, WB ARG41099
Rabbit anti-ACE2 pAb (N-terminus) Hu ELISA, ICC/IF, IHC, WB ARG54914
Rabbit anti-ACE2 pAb (C-terminus) Hu, Ms, Rat ELISA, ICC/IF, IHC-Fr, IHC-P, WB ARG54913
Rabbit anti-ACE2 pAb (Center) Hu ICC/IF, IHC-P, WB ARG55800

 

● ACE2 proteins

Product  Expression Cat. No.
Human ACE2 protein (ECD) HEK293 cell ARG70351
Human ACE2 protein (ECD) (Fc-fused) HEK293 cell ARG70350
Human ACE2 protein (Fc-fused) CHO cell ARG70225

 

● ELISA kits for ACE2 research

ACE2 shedding
Human ACE2 ELISA Kit
(ARG80959)

Sensitivity: 31 pg/ml
Sample: Serum, plasma, cell culture supernatant

ACE2 deficiency
Human Angiotensin II ELISA Kit
(ARG80961)

Sensitivity: 2 pg/ml
Sample: Serum, plasma, cell culture supernatant, homogenate

ACE2 deficiency
Human Angiotensin 1-7 ELISA Kit
(ARG80960)

Sensitivity: 2 pg/ml
Sample: Serum, plasma, cell culture supernatant


 

● Nucleocapsid protein ●

The nucleocapsid protein is a structural protein required for genomic RNA packaging. It is the most abundant protein in coronavirus and often used as a marker in diagnostic assays.

 

● Nucleocapsid antibodies

Product  Clonality Application Cat. No.
SARS-CoV / SARS-CoV-2 Nucleocapsid antibody [SQab20177] Human IgG1 ELISA, ICC/IF, WB ARG66735
SARS-CoV / SARS-CoV-2 Nucleocapsid antibody [SQab20179] Human IgM ELISA, FACS, ICC/IF, WB ARG66742
SARS-CoV / SARS-CoV-2 Nucleocapsid antibody [SQab20180] Human IgA ELISA, FACS, ICC/IF, WB ARG66741
SARS-CoV / SARS-CoV-2 Nucleocapsid antibody [SQab20210] Mouse mAb ELISA, ICC/IF, WB ARG66782
SARS-CoV / SARS-CoV-2 Nucleocapsid antibody [SQab20212] Mouse mAb ELISA, ICC/IF, WB ARG66796
SARS-CoV / SARS-CoV-2 Nucleocapsid antibody Rabbit pAb WB ARG42478

 

● Nucleocapsid proteins

Product  Expression Cat. No.
SARS-CoV-2 Nucleocapsid protein (Tag free) E. coli ARG70217
SARS-CoV-2 Nucleocapsid protein HEK293 cell ARG70216
SARS-CoV Nucleocapsid protein HEK293 cell ARG70215

 

● Nucleocapsid ELISA kit

Product  Sensitivity Sample Cat. No.
SARS-CoV-2 Nucleocapsid protein ELISA Kit 0.171 ng/ml Cell culture supernatant, nasal swab, saliva ARG82823
SARS-CoV-2 Nucleocapsid protein ELISA Kit 1.56 ng/ml Serum, plasma, cell culture supernatant ARG82688

 

 

● E, M and NS proteins 

● E, M, NS protein antibodies

Product  Clonality Application Cat. No.
SARS-CoV-2 E protein antibody Rabbit pAb ELISA, IHC-P, WB ARG43205
SARS-CoV M protein antibody Rabbit pAb ELISA, WB ARG54884
SARS-CoV RdRp R2 antibody [4E6] Mouse mAb WB ARG11093
SARS-CoV NSP8 antibody [5A10] Mouse mAb ICC/IF, WB ARG11095
SARS-CoV-2 NSP5/3CLpro antibody Rabbit pAb ELISA, IHC-P, WB ARG43303

 

● E & ORF8 proteins

Product  Expression Cat. No.
SARS-CoV-2 Envelope protein E. coli ARG70346
SARS-CoV-2 ORF8 protein HEK293 ARG70356

 

 

● More Coronavirus reagents 

● Antibodies

Product  Clonality Application Cat. No.
MERS-CoV Spike antibody Goat pAb WB ARG42526
MERS-CoV Nucleocapsid antibody [7H6] Mouse mAb ELISA, ICC/IF, IP, WB ARG11090
Bovine Coronavirus Surface antibody [5A4] Mouse mAb ELISA ARG10284
Feline Coronavirus antibody [FIPV3-70] Mouse mAb ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, WB ARG22654

 

● Proteins

Product  Expression Cat. No.
MERS-CoV Nucleocapsid protein HEK293 cell ARG70214
HCoV-NL63 Nucleocapsid protein HEK293 cell ARG70213
HCoV-OC43 Nucleocapsid protein E. coli ARG70221
HCoV-HKU1 Nucleocapsid protein E. coli ARG70222
HCoV-229E Nucleocapsid protein E. coli ARG70223

 

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SARS-CoV-2 life cycle